Morphological change in endothelial cells is an initial and crucial step in the process of establishing a functional vascular network. Following or associated with differentiation and proliferation, endothelial cells elongate and assemble into linear cord-like vessels, subsequently forming a perfusable vascular tube.

What is the morphology of endothelial cells?

Morphological change in endothelial cells is an initial and crucial step in the process of establishing a functional vascular network. Following or associated with differentiation and proliferation, endothelial cells elongate and assemble into linear cord-like vessels, subsequently forming a perfusable vascular tube.

How many types of endothelial cells are there?

Our comprehensive endothelial cell culture portfolio consists of 12 different types of large vessel and microvascular human endothelial cells with optimized growth media for each cell type.

What organelles are in endothelial cells?

Perinuclear cytoplasm of endothelial cells contains most of the mitochondria and other organelles, such as the Golgi apparatus. The peripheral cytoplasm is scarce and has few organelles, although endoplasmic reticulum tubules can be found close to the plasma membrane.

How big are endothelial cells?

The shape of the endothelial cells varies across the vascular tree, but they are generally thin and slightly elongated, their dimension being roughly 50–70 μm long, 10–30 μm wide and 0.1–10 μm thick.

What is characteristic of endothelial cells?

Endothelial cells form barrier between blood and smooth muscle cells, playing crucial role in regulation of vasomotorics, hemostasis, angiogenesis, inflammatory processes and immunology.

What is the main function of endothelial cells?

The endothelium is a thin membrane that lines the inside of the heart and blood vessels. Endothelial cells release substances that control vascular relaxation and contraction as well as enzymes that control blood clotting, immune function and platelet (a colorless substance in the blood) adhesion.

What type of cell is an endothelial cells?

Endothelial cells form a single cell layer that lines all blood vessels and regulates exchanges between the bloodstream and the surrounding tissues. Signals from endothelial cells organize the growth and development of connective tissue cells that form the surrounding layers of the blood-vessel wall.

What kind of cells are endothelial cells?

The endothelium is a thin layer of single flat (squamous) cells that line the interior surface of blood vessels and lymphatic vessels. Endothelium is of mesodermal origin. Both blood and lymphatic capillaries are composed of a single layer of endothelial cells called a monolayer.